Four patients were extricated from an SUV at the scene. Three pediatric patients were reported at the scene, with ages listed as 18 months old; 13 years old; and 16 years old. A 35-year-old woman was also injured.

LAFD Captain Erik Scott said a high-speed collision occurred in the intersection of Main Street and 111th Place, pushing the vehicles southbound. At least one vehicle made contact with a building.

LAFD and LAPD officers responded just before 8 a.m. Monday.

A silver Mercedes sedan and a silver SUV were involved in the crash. The sedan was engulfed in flames upon firefighters’ arrival, and it was quickly extinguished, Scott said.

The SUV had four people inside. A 35-year-old mother was driving and a 16-year-old girl was in the passenger seat. In the rear of the SUV were an 18-month-old boy and a 13-year-old boy.

The two children in the rear of the SUV were in cardiac arrest due to traumatic injuries from the crash, Scott said. Paramedics performed CPR at the scene, and both children were transported to a local hospital in grave condition.

The other two victims were hospitalized in critical condition.

Capt. Scott said the sedan was empty when first-responders arrived. It was believed there was a single driver.
The crash scene was under investigation by the LAPD.

An unidentified male was reportedly seen by witnesses running from the scene with a limp.